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Portfolio Architecture

Our portfolio architecture practice builds internal and external product opportunities onto structural core competencies to establish portfolio critical mass, a robust product pipeline, and a synergistic product mix.

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Representative context of our portfolio architecture engagements includes:

  • Achieving premium valuation levels correlated with improving earnings volatility and sensitivity to individual product success
  • Prioritization of the multiple lead and pipeline product/indication/market opportunities addressable with internal platform technologies
  • Strategic initiatives that target high-value business spaces
  • Partnering and strategic alliances
  • In-licensing and out-licensing
  • Restructurings, including mergers, acquisitions, diversifications, and joint ventures

Representative scope of our portfolio architecture engagements can include:

  • Multiphase external opportunity targeting and acquisition, from: specification of opportunity attributes; through identification of potential alliance, acquisition, licensing, and investment opportunities; through multiphase diligence and deal valuation, structure, and closure
  • Multiphase internal opportunity prioritization and analysis, from feasibility, development, market, commercial, and financial analyses through matrix-based portfolio representations
  • Client enterprise core competency and strategy explication
  • Comprehensive external opportunity searching, including private equity, corporate, trade, professional, scientific, technology transfer, sponsored research, and patent database mining, literature reviewing, and executive interviewing
  • Unmet medical needs identification, and clinical and technology environment forecasting for targeted business spaces
  • Multiphase diligence, planning, forecasting of selected opportunities
  • Pro forma opportunity and portfolio financial modeling, including forecasts of enterprise earnings, earnings dilution, and cash flow
  • Multi-scenario equity and debt-financed capital structure and balance sheet forecasting
  • State-of-the-art modeling of shareholder value employing discounted cash flow (including program IRR and firm FCFF), real options (including compound and switching options), and comparable (including milestone-based) methodologies

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