Portfolio Architecture
Our portfolio architecture practice builds internal
and external product opportunities onto structural core competencies
to establish portfolio critical mass, a robust product pipeline,
and a synergistic product mix.

Representative context of our portfolio architecture
engagements includes:
- Achieving premium valuation levels
correlated with improving earnings volatility and sensitivity
to individual product success
- Prioritization of the multiple lead
and pipeline product/indication/market opportunities addressable
with internal platform technologies
- Strategic initiatives that target high-value
business spaces
- Partnering and strategic alliances
- In-licensing and out-licensing
- Restructurings, including mergers,
acquisitions, diversifications, and joint ventures
Representative scope of our portfolio architecture
engagements can include:
- Multiphase external opportunity targeting
and acquisition, from: specification of opportunity attributes;
through identification of potential alliance, acquisition,
licensing, and investment opportunities; through multiphase
diligence and deal valuation, structure, and closure
- Multiphase internal opportunity prioritization
and analysis, from feasibility, development, market, commercial,
and financial analyses through matrix-based portfolio representations
- Client enterprise core competency and
strategy explication
- Comprehensive external opportunity
searching, including private equity, corporate, trade, professional,
scientific, technology transfer, sponsored research, and
patent database mining, literature reviewing, and executive
interviewing
- Unmet medical needs identification,
and clinical and technology environment forecasting for
targeted business spaces
- Multiphase diligence, planning, forecasting
of selected opportunities
- Pro forma opportunity and portfolio
financial modeling, including forecasts of enterprise earnings,
earnings dilution, and cash flow
- Multi-scenario equity and debt-financed
capital structure and balance sheet forecasting
- State-of-the-art modeling of shareholder
value employing discounted cash flow (including program
IRR and firm FCFF), real options (including compound and
switching options), and comparable (including milestone-based)
methodologies
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